SaMD Development

The AI and UX Behind Medical Device Software

You bring the device concept and regulatory strategy. We bring the AI engine, the clinical interface, and the healthcare workflow integration. Digital Scientists builds the intelligence layer and user experience for SaMD products, with quality partners handling FDA documentation and submission.

Guardian AI-powered operating room monitoring

Guardian. AI-powered OR monitoring built with SaMD principles

Guardian / Vigilant Medical
CommuniCare
Duke Health
Easterseals
The Challenge

SaMD needs two things most teams can't do at once: build great AI and navigate FDA.

The SaMD market is projected to reach $167 billion by 2032. The FDA has cleared hundreds of AI/ML-enabled devices. But building SaMD requires two fundamentally different skill sets: the engineering team that builds production AI and clinical-grade interfaces, and the regulatory team that manages QMS, design controls, and FDA submissions. Most companies struggle to find both in one partner. We solve one half of that equation, and bring a quality partner for the other.

3-5x

The cost multiplier of retrofitting regulatory compliance into finished software. Building with IEC 62304 and design controls from day one isn't optional. It's economics.

$167B

Projected SaMD market by 2032 (23.6% CAGR). AI-powered diagnostics, monitoring, and digital therapeutics are driving explosive growth.

100s

of AI/ML-enabled SaMD devices cleared by the FDA. The regulatory pathway exists, the challenge is building software worthy of it.

What We Build

The AI Engine and Clinical Interface for SaMD

We focus on what we do best: building the intelligence layer and user experience that makes SaMD products work in clinical environments.

AI / ML Development

Diagnostic algorithms, anomaly detection, risk stratification models, image analysis, and predictive analytics. Production-grade AI trained on clinical data with explainable, audit-defensible outputs.

10+ years healthcare AI, $20M+ verified ROI

Clinical UX & Human Factors

IEC 62366 usability engineering, because the interface is as regulated as the algorithm. Workflow-driven design for clinicians, patients, and operators. Accessibility built in.

Formative & summative usability testing

Data & Integration

Data pipelines, EHR integration, cloud infrastructure, and real-time processing. HL7 FHIR, CCDA, and custom API connectors. HIPAA-compliant from day one.

PointClickCare, Epic, Gehrimed, custom

What We Partner On: FDA Regulatory & QMS

For regulatory documentation, QMS (ISO 13485), Design History Files, risk management files (ISO 14971), and FDA submissions (510(k), De Novo, PMA), we work with specialized quality partners. This isn't a gap; it's a deliberate structure. You get deep AI and UX expertise from us, and deep regulatory expertise from a team that does nothing else.

DS Builds

AI/ML, UX, Data, Integration

Partner Handles

QMS, DHF, FDA Submission

You Own

Device Concept, Clinical Strategy

Applications

Types of SaMD We Build

CLASS II

Diagnostic Software

AI-powered screening, image analysis, risk assessment algorithms that aid clinical diagnosis. The intelligence layer that makes the device smart.

Monitoring Applications

Real-time vital sign monitoring, anomaly detection, clinical alert systems. Built for RPM and operating room environments.

Digital Therapeutics

Software that delivers clinical interventions for conditions like diabetes management, mental health, chronic pain. The fastest-growing SaMD category.

Clinical Decision Support

Evidence-based recommendations and alerts at point of care. CDSS that supports but doesn't replace clinical judgment.

Regulatory Awareness

We Build With These Standards in Mind

Our development process is designed to produce software that meets regulatory requirements, even when the regulatory submission is handled by our quality partners.

IEC 62304

Medical device software lifecycle. We develop with safety classification, documented requirements, traceability, and verification/validation processes aligned to this standard.

ISO 14971

Risk management. We identify use-related hazards, implement risk controls in the UI and algorithm design, and document residual risks throughout development.

IEC 62366

Usability engineering and human factors. Formative and summative usability testing to ensure the interface doesn't introduce clinical risk.

ISO 13485

Quality Management System. Our quality partners maintain the QMS; we develop within its controls, design inputs, outputs, reviews, and change management.

FDA Cybersecurity

Threat modeling, secure architecture, encryption, access controls, and vulnerability management aligned to FDA premarket cybersecurity guidance.

HIPAA

Any SaMD handling PHI requires HIPAA compliance, encryption, audit trails, access controls, BAA compliance. Built in from day one.

Our Process

Regulatory-Aware Development

Our standard methodology adapted for SaMD, with design controls, traceability, and verification built into every phase.

Discover · Experiment · Engineer · Optimize

Phase I

Discover

What are we building?

01

Risk Classification

FDA class, intended use, regulatory pathway

02

User & Hazard Analysis

Clinical context, user needs, use-related risks

Phase II

Experiment

Does the approach work?

03

Prototype & Validate

AI model POC, UX prototype, usability test

04

Design Controls

Requirements, traceability, risk file initiated

Phase III

Engineer

Build it right.

05

IEC 62304 Development

Compliant software lifecycle

06

V&V Testing

Verification & validation, unit/integration/system

07

Usability Testing

IEC 62366 formative & summative

08

Clinical Validation

Performance testing, clinical evidence

Phase IV

Optimize

Maintain & improve.

09

Submission Support

Technical documentation for FDA filing

10

Post-Market

Monitoring, updates, change management

Why Partner With Us

Healthcare AI expertise applied to medical devices.

10+ years building production healthcare AI. The same team that built RAF/HCC coding optimization and ambient AI scribes can build the intelligence layer for your SaMD product.

10+ years healthcare AI

Production AI Expertise

ML models, NLP, computer vision, predictive analytics: all built for regulated healthcare environments.

$20M+ verified ROI

Healthcare-Proven

The same AI capabilities that power our healthcare solutions can be applied to SaMD products.

75 integrated team

Full-Stack Team

AI engineers, UX researchers, mobile developers, data engineers, one team from concept to clinical validation.

"By applying a robust machine learning model to our app, DS helped us create a scalable and accurate solution that met our rigorous clinical requirements."

Justin Scott, M.D., FASA

CEO, Vigilant Medical Solutions (Guardian)

Technology Stack

Built for Medical-Grade Software

Apple/iOS Android HL7 FHIR AWS Azure

AI / ML

PyTorch, TensorFlow, OpenAI, custom models, explainable AI

Mobile & Embedded

React Native, Swift, Kotlin, BLE/IoT device integration

Cloud & Security

AWS, Azure, HIPAA hosting, VPC isolation, FDA cybersecurity aligned

Have a medical device software concept?

30-minute call. No pitch. Just honest assessment of how we can help with the AI, UX, and engineering, and connect you with the right regulatory partner.

Understand your device concept and clinical context
Assess what AI and UX work is needed
Determine if there's a fit

Or call: 404.654.3855

Regulatory Compliance & Data Security

SaMD requires both FDA compliance and data security. We build with HIPAA, FDA cybersecurity guidance, and awareness of international requirements (MDR, CE marking) from day one. Retrofitting compliance costs 3-5x more than building it in.

Learn more about our compliance approach →
HIPAA Compliant
FAQ

Common Questions About SaMD Development

What is Software as a Medical Device (SaMD)?

SaMD is software intended for one or more medical purposes, diagnosis, treatment, prevention, or monitoring, that performs these purposes without being part of a hardware medical device. It runs on general-purpose platforms like mobile devices, web browsers, and cloud servers. The FDA regulates SaMD based on risk classification (Class I, II, or III).

What does Digital Scientists build for SaMD products?

We build the AI/ML intelligence layer and the clinical user interface. Diagnostic algorithms, monitoring systems, NLP, predictive models, and the UX that clinicians and patients interact with. For regulatory documentation and FDA submission (QMS, Design History Files, 510(k) submissions), we work with specialized quality partners.

What regulatory standards apply to SaMD?

Key standards: IEC 62304 (software lifecycle), ISO 14971 (risk management), IEC 62366 (usability/human factors), ISO 13485 (QMS), FDA cybersecurity guidance, and HIPAA for PHI-handling software. Building with these from day one costs 3-5x less than retrofitting.

How does AI fit into SaMD products?

AI powers diagnostic screening, image analysis, risk stratification, anomaly detection, and clinical decision support in SaMD. The FDA has cleared hundreds of AI/ML-enabled devices. DS brings 10+ years of healthcare AI, the same capabilities that power our RAF/HCC coding and clinical documentation AI.

What FDA classification applies to SaMD?

Class I (low risk, may be exempt), Class II (most common, requires 510(k) or De Novo), Class III (highest risk, requires PMA). The IMDRF framework categorizes by significance of information provided and seriousness of the healthcare situation.

What is IEC 62366 and why does it matter?

IEC 62366 is the standard for usability engineering in medical devices. It requires identifying use-related hazards and conducting usability testing. For SaMD, the interface design is as regulated as the algorithm, a usability error in a diagnostic tool can have the same consequences as an algorithmic error. Our healthcare UX team brings human factors expertise for this requirement.